To enhance the efficiency of neutralizing Houthi kamikaze drones, U.S. military forces have begun employing APKWS laser-guided missiles, which are integrated into F-16 fighter jets. Similarly, the Ukrainian military utilizes these missiles in their VAMPIRE air defense systems against Russian “Geran-2” drones. Recent footage from the Ukrainian Naval Forces showcases the successful engagement of these drones in the Odesa region using the VAMPIRE systems. This marks a continuation of previous intercepts, with the first confirmed engagement of a Russian drone by VAMPIRE occurring in February of the previous year, also in Odesa. The VAMPIRE system, mounted on a pickup chassis, utilizes the APKWS missiles, which are modifications of the widely used Hydra 70 unguided rockets, enhanced for precision through the addition of a laser guidance system. Designed for targeting small aerial threats and lightly armored ground vehicles, the VAMPIRE is a modular air defense solution adaptable to various platforms. The strategic significance of these developments lies in the increasing effectiveness of lower-cost, precision-targeting capabilities in contemporary conflict scenarios, enabling forces to counter aerial threats with greater efficiency and adaptability.